OVERVIEW

Eyenovia is a late-stage ophthalmic biopharmaceutical company developing breakthrough treatments for front and back-of-the-eye diseases, which are made possible by the company’s transformative, high precision ophthalmic delivery platform. Eyenovia’s pipeline is currently focused on the development of four programs including myopia (nearsightedness) progression, glaucoma and other eye diseases.

Eyenovia at a Glance

Watch a brief video about our technology

EYENOVIA MAKES NEW THERAPIES POSSIBLE

Our unique delivery platform uses breakthrough piezo-print technology for high-precision micro-dosing. Microdosing allows for fully effective therapies that may also avoid many tolerability and side-effect issues associated with traditional eye drop delivery.

Eyenovia’s Breakthrough Technology

THE EYENOVIA SOLUTION

Most conventional front-of-the-eye therapies are administered using 100-year-old eye-dropper technology, consistently overdosing the eye with 30-50 μL of pharmaceutical ingredients and toxic preservatives compared to the eye’s natural, physiologic tear film capacity of 7-8 μL. This overdose is associated with many ocular side effects such as hyperemia (eye redness), discomfort, dry eye, foreign body sensation, pigment discoloration, periorbital dermatitis and others. For some topical medications, there are also major cardiovascular side effects such as bradycardia and arrhythmia.


Eyenovia’s high precision microdosing delivers precicely 6-8 μL (the volume the eye can hold) in a targeted way, directly coating the corneal surface rather than the conjunctiva, thus reducing collateral tissue exposure and focusing on the cornea where 80% of intraocular drug penetration occurs. In addition, Eyenovia’s smart electronics and mobile e-health technology can track when patients administer doses. This will transform compliance and chronic disease management by empowering patients and physicians for the first time with access to dynamic, real time monitoring and compliance data for a more intelligent and personalized therapeutic paradigm.

Eyenovia is building a portfolio of superior ophthalmic therapeutics with its proprietary micro-dosing formulations of existing and new molecular entities. Eyenovia’s lead program is for the prevention of myopia (nearsightedness) progression. Progressive myopia is a serious, sight-threatening condition that may impact up to 5 million children in the United States alone and up to 80% of children in some countries in Asia. Using our unique platform technology, Eyenovia is preparing a single, de-risked Phase 3 study that may lead to the first FDA-approved treatment for this condition.

In addition to progressive myopia, the company is advancing programs for chronic angle closure glaucoma and mydriasis into Phase III clinical programs and preparing registration studies for an OTC product for dry eye. Eyenovia is expected to complete all three of these development programs through registration by 2020.

Find out more about how Eyenovia is making new therapies possible.
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Contact us for more information

Contact us today to learn more about how our microdosing technology is poised to transform
the standard of care in ophthalmic therapeutic delivery.

295 Madison Avenue, Suite 2400 NY 10017  +1 (917) 289-1117

[email protected]